U.S. companies were among the very first to do business in a newly independent Kazakhstan. The path these early American multinationals and investors first trudged has since 1991 worn well-trodden for other foreign investors, large companies, small- and medium- sized enterprises, and even startups. More than 700 American companies are successfully operating in Kazakhstan, including Chevron, Exxon Mobil, General Electric, Halliburton, etc.
Annual business and investment events are held between the two countries to promote economic cooperation. A delegation of 16 major U.S. businesses visited Kazakhstan in October 2018 during the first US Department of Commerce Certified Trade Mission to Kazakhstanled by Secretary Wilbur Ross. The trade mission resulted in agreements in aviation and space research, agriculture, the petrochemical industry and infrastructure development.